IPTG (isopropyl-β-D-thiogalactopyranoside) ≥98% (by HPLC on dried basis), Biotech Reagent, cGMP-manufactured, J.T.Baker®


Synonyms: (2R,3R,4S,5R,6S)-2-(Hydroxymethyl)-6-(isopropylthio)tetrahydro-2H-pyran-3,4,5-triol

Management of Change (MOC) category = R

V264-01 BAKRV264-05 V264-05 V264-02 BAKRV264-01 BAKRV264-02
CAJTV264-05CS 105426.99 CAD
CAJTV264-05 JTV264-05 CAJTV264-01 CAJTV264-02 JTV264-01 JTV264-02
IPTG (isopropyl-β-D-thiogalactopyranoside) ≥98% (by HPLC on dried basis), Biotech Reagent, cGMP-manufactured, J.T.Baker®
IPTG (Isopropyl-β-D-thiogalactopyranoside)

Reduce risk in your bioprocessing applications with Avantor J.T.Baker brand cGMP manufactured IPTG.

  • cGMP manufactured under ICHQ7
  • High-purity (>98% by HPLC)
  • Low microbial, trace metals and endotoxin content
  • Consistent lot-to-lot protein induction performance
  • TSE/BSE-free
  • 1,4-Dioxane-free

J.T Baker brand cGMP manufactured IPTG is performance tested to assure consistent lot-to-lot biological induction, and processed to remove and control product/process related impurities, with minimal lot-to-lot variability for improved protein expression.

Fully validated and documented through Batch Process Records (BPR) including analytical test data, stability protocol and impurity profile.

Packaging: Packaged in moisture permeation resistant controlled packaging.

Formula: C₉H₁₈O₅S
MW: 238.31 g/mol
Melting Pt: 110…122 °C
MDL Number: MFCD00063273
CAS Number: 367-93-1

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Specification Test Results

GMP Manufactured Product
Store and ship product between 2 and 8 °C
CAUTION: For Manufacturing, processing or repackaging
Appearance (white to off-white solid) Passes Test
Identification (IR) Passes Test
pH of 5% Solution 5.00 - 7.00
Specific Rotation @ 25 °C -34.5 - -28.5 Degree
Melting Point 110 - 122 °C
Water (H₂O), For Information Only
Purity (by HPLC) (anhydrous basis) ≥98 %
Assay (by HPLC) (anhydrous basis) 98 - 102
Endotoxin Concentration, EU/g
Residual Methanol ≤3000 ppm
Residual Ethanol ≤5000 ppm
Residual Isopropanol ≤5000 ppm
Residual Ethyl Acetate ≤5000 ppm
Total Aerobic Microbial Count ≤100 cfu/g
Total Yeast and Mold Count ≤100 cfu/g
Biological Induction Characterization (induction response @ 1mM)
Arsenic (As), For Information Only
Cadmium (Cd), For Information Only
Mercury (Hg), For Information Only
Lead (Pb), For Information Only
Cobalt (Co), For Information Only
Nickel (Ni), For Information Only
Vanadium (V), For Information Only
Silver (Ag), For Information Only
Gold (Au), For Information Only
Iridium (Ir), For Information Only
Osmium (Os), For Information Only
Palladium (Pd), For Information Only
Platinum (Pt), For Information Only
Rhodium (Rh), For Information Only
Ruthenium (Ru), For Information Only
Selenium (Se), For Information Only
Thallium (Tl), For Information Only
Barium (Ba), For Information Only
Chromium (Cr), For Information Only
Copper (Cu), For Information Only
Lithium (Li), For Information Only
Molybdenum (Mo), For Information Only
Antimony (Sb), For Information Only
Tin (Sn), For Information Only
Aluminum (Al), For Information Only
Iron (Fe), For Information Only
Manganese (Mn), For Information Only
Zinc (Zn), For Information Only
Residual Solvents: The Class 3 solvents Ethanol, Isopropanol, Ethyl
Acetate and the Class 2 solvent Methanol are likely to be present. These solvents are quantified and reported on each batch. No other
Class 1,2,3, or other solvents are used or produced in the production
process. Dioxane was not used in the manufacturing process.
Bacterial Induction characterization: Test performed at 1 mM of IPTG (E.
Coli. protein expression)
IPTG is highly hygroscopic. Allow packaging/container to equilibrate to
room temperature before opening for analysis. Ensure sample is kept dry
(such as in a desiccator) after opening.

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